The global demand for Mixed Mode Chromatography Resin Market is presumed to reach the market size of nearly USD 198.33 MN by 2030 from USD 103.27 MN in 2022 with a CAGR of 8.5% under the study period of 2023 - 2030. Regarding volume, the market was calculated XX Thousand Liters in 2022 and forecast to touch XX Thousand Liters by 2030 with a CAGR of XX% during 2023-2030.
Mixed-mode chromatography resin refers to a chromatographic medium or stationary phase employed for the separation and refinement of biomolecules like proteins, nucleic acids, and peptides. Its distinct feature lies in its capacity to incorporate various interaction modes within a single chromatography resin particle, providing enhanced selectivity and adaptability when isolating desired molecules from intricate mixtures.
Market Dynamics
The mixed-mode chromatography resin market is experiencing significant growth driven by multiple factors. This specialized chromatography technology is finding increasing applications in biopharmaceuticals, biotechnology, and research due to its versatility and high selectivity. One of the primary drivers is the burgeoning biopharmaceutical industry, which demands efficient purification processes for complex biomolecules like monoclonal antibodies and vaccines. Mixed-mode resins are highly adaptable, allowing for customized separation strategies by adjusting parameters like pH and ligand chemistry, catering to the specific needs of purification processes. Mixed-mode chromatography plays a crucial role in purifying and analyzing diverse biomolecules in research fields such as genomics and proteomics. Additionally, the need for cost-effective and time-efficient bioprocessing in pharmaceutical manufacturing encourages the use of mixed-mode resins to simplify purification steps. Furthermore, regulatory compliance and the rising interest in emerging therapies like gene and cell-based therapies contribute to the adoption of mixed-mode resins. Advancements in chromatography technology, sustainability concerns, and the global expansion of biotechnology also fuel market growth. As biopharmaceutical and biotechnology sectors continue to evolve, mixed-mode chromatography resins are poised to remain a vital component of purification processes, ensuring high specificity and efficiency in biomolecule separation and purification.
The report covers Porter’s Five Forces Model, Market Attractiveness Analysis, and Value Chain analysis. These tools help to get a clear picture of the industry’s structure and evaluate the competition attractiveness at a global level. Additionally, these tools also give an inclusive assessment of each segment in the global market of mixed mode chromatography resin. The growth and trends of Mixed Mode Chromatography Resin Industry provide a holistic approach to this study.
Market Segmentation
This section of the mixed mode chromatography resin market report provides detailed data on the segments by analyzing them at country and regional level, thereby assisting the strategist in identifying the target demographics for the respective product or services with the upcoming opportunities.
By Technique
- Ion Exchange - Hydrophobic
- Hydroxyapatite
- Others
By End-Use
- Pharmaceutical And Biotechnology
Regional Analysis
This section covers the regional outlook, which accentuates current and future demand for the Mixed Mode Chromatography Resin market across North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa. Further, the report focuses on demand, estimation, and forecast for individual application segments across all the prominent regions.
Global Mixed Mode Chromatography Resin Market Share by Region (Representative Graph)

The research report also covers the comprehensive profiles of the key players in the market and an in-depth view of the competitive landscape worldwide. The major players in the mixed mode chromatography resin market include GE Healthcare Lifesciences, Merck KGaA, Tosoh Corp, Purolite Corp, Danaher Corp, and Bio-Rad Labs. This section consists of a holistic view of the competitive landscape that includes various strategic developments such as key mergers & acquisitions, future capacities, partnerships, financial overviews, collaborations, new product developments, new product launches, and other developments.
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